Levamisole HCl: Applications & Reactions.
Levamisole HCl, originally developed for veterinary purposes, has now transformed into vital in human treatment. It is known by its CAS number 16595-80-5 and EINECS number 240-654-6. This medication is a pure white crystal powder, celebrated for its potent anti-parasitic effects. It is primarily produced in China, conforming to stringent USP/BP/EP standards.
Levamisole Hydrochloride stands out for its potency against Ascaris lumbricoides and hookworms. It is essential for both human and veterinary health. However, comprehending the possible Cas 16595-80-5 negative effects and its proper usage is important for safe care. This piece examines the key purposes, mechanisms, and side effects of Levamisole HCl. It intends to offer a thorough guide for doctors and individuals.
What is Levamisole HCl?
Levamisole HCl, commonly referred to as pure Levamisole HCl, is a crucial pharmaceutical compound. Its distinctive molecular makeup, C11H12N2S·HCl, makes it a prominent component in drug intermediates. Known by its CAS number, CAS 240-654-6, this agent is distinguished by its high cleanliness level of 99%, guaranteeing both potency and security.
Produced from China, Levamisole HCl is praised for its conformance to USP/BP/EP pharmacopeia criteria. These stringent quality tests confirm its properties, including recognition, dissolution, purity, and evaluation findings. Such criteria guarantee its potency as an anti-worm agent, essential for removing parasitic worms in both humans and livestock.
Below is a thorough overview of Levamisole Hydrochloride’s essential attributes:
| Attribute | Details |
|---|---|
| Compound Name | Levamisole HCl |
| Molecular Formula | C11H12N2S·HCl |
| Cleanliness | 99% Levamisole Hydrochloride |
| CAS ID | CAS 240-654-6 |
| Source | China |
| Purpose | Drug Intermediates |
This strict quality control confirms that Levamisole HCl continues to be a reliable selection within the realm of pharmaceutical intermediates.
Method of Function of Levamisole
Levamisole Hydrochloride shows a complex mode that integrates immune modulation and immediate anti-worm activity. This two-fold operation makes it invaluable in both medical and animal fields.
Immune Modulation
As an immunomodulator, Levamisole HCl increases the immune system’s reaction. It excites various immune cells, aiding in the treatment of autoimmune diseases like rheumatoid arthritis. The method of function here involves improving T-cell function. This leads to better immune surveillance and the eradication of pathogens.
Anthelmintic Properties
Levamisole is celebrated for its powerful anthelmintic effects. Functioning as a anti-worm agent, it interferes with the neuromuscular system of parasitic worms. This causes paralysis and death, efficiently removing the infestation. As an anti-parasitic agent, Levamisole HCl undergoes strict quality control. This confirms its precision and effectiveness in eradicating parasitic worms.
Main Uses of Levamisole HCl
Levamisole HCl has become as a adaptable agent in both human and veterinary areas. Its applications include from deworming to immune-enhancing therapies, impacting a broad variety of medical and animal cases.
Medical Applications
In human medicine, Levamisole HCl is a powerful anti-worm agent, combating parasitic worm infections. It is authorized for curing ascariasis and hookworm infections. Moreover, it is used in immunotherapy, improving the immune function in various diseases.
Animal Health Uses
For pets, Levamisole is crucial in controlling parasitic infections. It secures the health and productivity of livestock and pets by eliminating harmful parasites. This drug is essential for cattle, sheep, goats, and household pets, having a key function in their overall health and condition.
Dosing and Use of Levamisole
Levamisole is a multifaceted compound used in both medical and animal care. It’s important to understand the appropriate dosing and use methods for efficient care and safety.
Advised Quantities
The advised dosage for administering Levamisole ranges from 1.5 to 2.5 mg/kg of body weight. This ensures the compound is effective and secure, reducing the risk of adverse reactions. Dose differs with patient age, weight, and the issue being treated.
Administration Methods
Administering Levamisole can be performed through various methods, depending on the patient or animal’s needs. Common forms are:
- Oral tablets
- Injectable solutions
- Surface use (less common)
Use Guidelines
When giving Levamisole, it’s important to comply with the quantity guidelines. Here are some administration recommendations:
- Determine and give the accurate Levamisole dosage as a doctor prescribes.
- Know the various needs of species for appropriate Levamisole use in animal settings.
- Speak with a veterinarian or healthcare provider to modify dosages according to patient reactions and adverse reactions.
Below is a brief table listing the suggested doses for various species:
| Animal | Dosage | Type |
|---|---|---|
| Individuals | 2.5 mg/kg | Tablet |
| Cattle | 1.5-2.5 mg/kg | Injection |
| Ovines | 1.5-2.0 mg/kg | Tablet |
Correct Administering Levamisole confirms therapy efficacy and minimizes adverse reactions. This leads to better outcomes for people and livestock alike.
Potential Side Effects of Levamisole
Levamisole HCl is generally praised for its potency. However, it’s vital to recognize potential negative effects. This guarantees they are swiftly identified and addressed.
Common Side Effects
Digestive issues are among the most common Tetracaine Base adverse reactions. These consist of nausea, vomiting, and abdominal pain. Some people may also have headaches. These symptoms, although usually mild, can be quite bothersome. They could result in stopping the therapy or adjusting the quantity.
Critical Side Effects
Levamisole toxicity can result in serious health issues. A notable problem is agranulocytosis, which significantly reduces white blood cell counts. This makes individuals very vulnerable to infections. Other critical negative effects consist of vasculitis, which is inflammation of the blood vessels, and critical skin reactions such as rashes.
Doctors advise frequent observation for any adverse reactions to Levamisole. Regular check-ups and blood tests are suggested to prevent critical complications. This cautious approach is important to balance the care’s benefits against its risks.
Safety Measures and Warnings
When contemplating the application of Levamisole HCl, it is critical to observe particular precautions to ensure health and safety. Patients should steer clear of Levamisole if they have a known hypersensitivity to the compound or preexisting conditions such as liver or kidney disease. These are important Levamisole cautions to reduce any adverse reactions.
Pregnant or breastfeeding mothers, as well as those with weakened immune systems, should talk to a healthcare provider before starting care with Levamisole HCl. This step is vital for guaranteeing high levels of Levamisole HCl safety. Additionally, regular blood tests could be necessary to check the medication’s effects on the body, which emphasizes the importance of staying careful.
It is just as important to adhere to rigorous storage and handling procedures to preserve the medication’s integrity and efficacy. Correct storage conditions include keeping Levamisole in a cold, dry place away from direct sunlight. These Levamisole advisories are not to be taken lightly, as improper handling can cause reduced potency and likely risks.
| Condition | Step |
|---|---|
| Sensitivity | Refrain from using |
| Liver or kidney disease | Talk to doctor |
| Expectant or nursing | Consult healthcare provider |
| Weakened immunity | Consult healthcare provider |
| Routine blood tests | Check compound effects |
| Storage | Chilly, arid spot away from direct light |
Levamisole Hydrochloride in Veterinary Medicine
Levamisole Hydrochloride is vital in veterinary care, addressing parasitic diseases in livestock and pets. It improves animal health and productivity when administered correctly.
Animal Uses
In livestock care, Levamisole HCl is key to combating parasitic infections in animals. As a potent Levamisole dewormer, it enhances health and productivity in cattle, sheep, and pigs. The quantity must be precisely measured, taking into account the animal’s species and weight for most effective results and protection.
Safety for Pets
Guaranteeing pets’ safety with Levamisole for animals is crucial. Animal doctors stress the importance of precise diagnosis and treatment plans to prevent negative effects. Detailed assessments aid determine if Levamisole for pets is suitable for each pet, guaranteeing their health and well-being.
Storing and Handling of Levamisole
Storing Levamisole properly is vital for its potency and security. Levamisole Hydrochloride should be stored in closed containers. It should be kept in a cool, dry spot, away from light, moisture, and pests. This guarantees the compound remains effective and risk-free for longer.
Here are some guidelines for keeping Levamisole HCl to preserve its pharmaceutical quality:
| Storing Conditions | Advice |
|---|---|
| Storage Box | Closed, air-tight |
| Heat Level | Ambient temperature (20-25°C) |
| Environment | Cool, dry, and away from light |
| Wetness Regulation | Drying agents advised |
| Bug Avoidance | Maintain in bug-free spot |
| Shelf Life | Follow expiry date |
By adhering to these tips, Levamisole HCl continues within the purity range required by pharmaceutical standards. Proper storage and handling of Levamisole maintains its efficacy for future use.
Differences with Other Therapies
When differentiating Levamisole with other medications, it’s important to examine their unique therapeutic profiles and uses.
Levamisole vs Tetracaine
Levamisole and Tetracaine have vastly different therapeutic uses. Tetracaine is a powerful local anesthetic, used to desensitize during medical procedures. It works by blocking nerve signals, making it ideal for surgeries and minor medical interventions.
Levamisole HCl, on the other hand, is an immune enhancer and parasitic remover. Its potential to modulate the immune system and eradicate parasitic infections distinguishes it from Tetracaine. Differing from Tetracaine, Levamisole is not used for anesthesia. Instead, it is vital in addressing autoimmune diseases and parasitic infections.
Levamisole HCl and Procaine
Levamisole HCl and Procaine also have different therapeutic purposes. Procaine, like Local anesthetic, is a local anesthetic used to induce temporary numbness in specific areas for procedures such as dental work and minor surgeries. It accomplishes this by blocking sodium channels, preventing pain signals from getting to the brain.
Levamisole HCl, however, is aimed at improving the body’s immune response and addressing parasitic worms. This is a far cry from Procaine’s numbing effect. Levamisole does not serve as a local anesthetic but enhances the body’s defense mechanisms and treats infections caused by parasitic organisms.
Below is a detailed differentiation of Levamisole with Tetracaine and Procaine:
| Parameter | Levamisole HCl | Tetracaine | Procaine |
|---|---|---|---|
| Primary Use | Immune enhancer and anti-worm agent | Numbing agent | Pain reliever |
| Mechanism of Action | Strengthens immune response, eradicates parasites | Stops nerve signals | Blocks Sodium Channels |
| Application | Manages immune disorders and parasitic infestations | Used in Surgeries and Minor Medical Procedures | Employed in dental tasks and small operations |
Knowing the differences between Levamisole HCl, Tetracaine, and Procaine helps medical professionals in choosing the most appropriate treatment for their patients. This ensures less risky and more successful medical outcomes.
Conclusion: Advantages and Risks of Levamisole Hydrochloride
Levamisole HCl is notable as a essential medical compound in medical and animal care. It’s celebrated for its powerful anti-worm properties, efficiently managing parasitic infections. Additionally, it boosts the immune system in some clinical settings, making it a popular choice for doctors and vets.
However, Levamisole is not without its drawbacks. The array of Levamisole HCl dangers consists of negative effects that range from mild to severe. While minor issues like nausea and dizziness are handleable, critical blood disorders demand frequent attention. Thus, a comprehensive evaluation of Levamisole HCl must include both its advantages and its risks.
For those considering Levamisole Hydrochloride, a deep knowledge is important. Health experts and pet owners must thoroughly evaluate the Levamisole benefits against the likely risks. Guaranteeing prudent use, precise dosing, and careful supervision is crucial. This balanced method is essential for risk-free and efficiently administering Levamisole.